Yeast extract, relieves animal stress

      The application of yeast extract in animal husbandry has formed a scientific system, and its multidimensional efficacy has been verified through a large amount of experimental data. The following will elaborate on specific animal categories and illustrate their mechanisms of action and actual effects through case studies:

1、 Mammals: Improving digestive efficiency and disease resistance

1. Piglets: an efficient alternative to plasma protein

      Weaned piglets are prone to diarrhea and growth inhibition due to immature intestinal development. Experiments have shown that replacing an equal amount of plasma protein powder with 1.5% beer yeast extract can increase the daily weight gain of piglets by 12.3% (P<0.05) and reduce feed conversion rate by 17.3% from 15-28 days. The core mechanism lies in:

      Highly digestible protein supply: The protein digestibility of native yeast extract reached 90.1%, significantly higher than that of beer yeast (77.5%), and 88% of peptides had a molecular weight less than 3.6 kDa, making them more easily absorbed by young animals.

      Optimization of intestinal morphology: The height of duodenal villi increased by 18.7%, the depth of crypts decreased by 12.4%, and the ratio of villi height to crypt depth increased by 23.5%, significantly enhancing nutrient absorption capacity.

2. Sows: Relieve lactation stress

      Adding 2kg/t yeast culture to the diet of lactating sows can increase weaning litter weight by 3-5kg and shorten the interval between weaning and estrus by 1-2 days. Its functional pathway includes:

      Immune regulation: Serum IgG levels increase by 15.8%, reducing the risk of lactation disorders caused by mastitis.

      Metabolic improvement: By regulating liver fatty acid metabolism, the milk fat percentage increased by 1.2 percentage points and the milk protein content increased by 0.8%.

2、 Poultry: dual effects of anti coccidiosis and growth promotion

1. Broiler: Enhance stress resistance and meat quality

      In the coccidiosis infection model, adding 500g/t nucleotide yeast extract can make broiler chickens:

      Immune organ development: The weight of the bursa of Fabricius increased by 13.4% (P=0.04), the chest muscle rate increased by 15.5%, and the leg muscle rate increased by 16.5%.

      Oxidative protection: Serum glutathione peroxidase activity increased by 28.7%, malondialdehyde content decreased by 31.2%, reducing muscle oxidative damage.

2. Egg laying hens: reduce the risk of vertical transmission

      In the experiment of Salmonella prevention and control, yeast culture reduced the positive detection rate of Salmonella in laying hens by 64% and the carrier rate of eggs by 58%. Its mechanism of action includes:

      Microbial regulation: The number of lactobacilli in the cecum increases by 2.1 times, inhibiting the colonization of pathogenic bacteria.

      Antibody Enhancement: The titer of Newcastle disease antibodies increased by 1.5 log2 units, and the vaccine protection rate increased by 9%.

3、 Aquatic products: Combination of antitoxin and growth promotion

1. Fish: Relieve the threat of fungal toxins

      Yeast cell wall extracts have shown significant effects in California bass farming in response to the combined contamination of aflatoxin (AFB1) and vomitoxin (DON):

      Toxic adsorption: The residual AFB1 in the liver decreased by 42.6%, and the intestinal DON binding rate reached 68.3%.

      Immune repair: Serum lysozyme activity increased by 37.2%, intestinal Clostridium/Proteobacteria ratio optimized by 29.5%, restoring intestinal barrier function.

2. Crustaceans: Enhance flavor and disease resistance

      Adding 5kg/t yeast functional protein (Prosaf) to Chinese mitten crab farming ®） Can be achieved:

      Edible visceral development: The liver and pancreas index increased by 22.3%, and the crude protein content of the gonads increased by 13.96%, significantly improving the quality of "ointment and fat".

      Antioxidant enhancement: The activity of superoxide dismutase (SOD) increased by 24.1%, and the activity of catalase (CAT) increased by 18.7%, alleviating oxidative stress during molting.

3. Ruminators: a powerful tool for coping with heat stress

      In the heat stress model of dairy cows, adding yeast culture (Ke Li Ben) can:

      Production performance: Daily milk production increased by 0.86kg, milk fat percentage increased by 0.3 percentage points, and dry matter intake increased by 5.2%.

      Rumen regulation: The number of fiber degrading bacteria increased by 1.8 times, volatile fatty acid production increased by 12.7%, and energy utilization efficiency was optimized.

4、 Mechanism of Action and Data Support

Immune activation network

      Innate immunity: β -1,3/1,6-glucan activates macrophages, leading to a 2.3-fold increase in nitric oxide (NO) secretion and a 45% increase in phagocytic index.

      Specific immunity: Nucleotides promote T lymphocyte proliferation, and the antibody titer against Newcastle disease in broiler chickens increases by 1.5 log2 units.

Intestinal microbiota balance

      Barrier function: Yeast cell wall mannan adsorbs intestinal pathogens, reducing the number of Escherichia coli in piglets by 63%.

      Nutritional metabolism: Yeast extracts with a high proportion of small peptides (<1kDa) can increase the gastric protease activity of Procambarus clarkii by 29%.

Anti stress system

      Oxidative protection: Glutathione (GSH) content increased by 35%, reducing the dehydration loss rate of broiler muscle caused by high temperature (from 8.7% to 6.2%).

      Hormonal regulation: By inhibiting the activity of the HPA axis, the cortisol level in piglets is reduced by 22%, alleviating weaning stress.

5、 Economic Benefit Analysis

cost optimization

      Replacing fish meal: Adding 3% yeast culture to shrimp feed can reduce the amount of fish meal by 4% without affecting growth performance, and reduce feed costs by 120 yuan per ton.

      Reduce medication: Chicken farms using yeast culture have seen a 40% decrease in antibiotic usage and a 28% reduction in veterinary drug costs.

input-output ratio

      Broiler farming: Adding 1.5% yeast extract can increase the economic benefits of each chicken by 15.4%, with an input-output ratio of 1:4.2.

      Aquaculture: Adding 500mg/kg yeast immunopolysaccharides to grass carp feed resulted in a relative immune protection rate (RPS) of 68% and reduced losses caused by bleeding by over 30%.

6、 Application precautions

Dose gradient design

      The optimal addition amount for broiler chickens is 0.5% -1.5%. Excess (>2%) may lead to elevated uric acid levels due to nucleotide metabolism burden.

      Aquatic animals need to be adjusted according to the farming density: 5kg/t is recommended for high-density shrimp farming, and the density can be reduced to 2.5kg/t for low-density shrimp farming.

Compatibility synergy effect

      Combined use with enzyme preparations: Xylanase and yeast extract can further increase the energy utilization efficiency of broiler chickens by 5.6%.

      Combined with probiotics: yeast culture and Bacillus subtilis increased the abundance of beneficial bacteria in the intestinal tract of laying hens by 37%.

Process adaptation

       High temperature granulation: Using microcapsule coating technology, the activity retention rate of yeast extract was increased from 42% to 81% after granulation at 85 ℃.

       Liquid feed: spray drying product is selected, and its dispersivity in water reaches 98%, so as to avoid blocking the pipeline by sedimentation.

      Yeast extract forms a complete solution in improving animal production performance, reducing breeding costs, and ensuring product quality through a multi-target mechanism of action. Its application has evolved from a single nutritional supplement to a systematic engineering covering immune regulation, environmental stress response, and intestinal health maintenance, becoming one of the core technologies of modern sustainable aquaculture.