What is allicin and what are its effects on animals什么是大蒜素?它对动物有什么影响
The main components of allicin are allicin, garlic oil, silicon dioxide, and calcium carbonate. It is a white powder with the unique aroma of garlic大蒜素的主要成分是大蒜素、大蒜油、二氧化硅和碳酸钙。它是一种白色粉末,带有大蒜的独特香气
Biological functions of allicin大蒜素的生物学功能
1. Allicin has strong antibacterial and anti-inflammatory effects, inhibiting or killing various cocci, bacilli, fungi, and viruses. Allicin has significant inhibitory or bactericidal effects on various pathogenic bacteria such as Staphylococcus aureus, meningitis, pneumococcus, streptococcus, diphtheria, dysentery, Escherichia coli, typhoid fever, paratyphoid fever, pertussis, tuberculosis, and cholera bacteria. The antibacterial principle of allicin is that the oxygen atom in allicin molecule binds with the thiol group in cysteine molecule, which is necessary for bacterial growth and reproduction, and inhibits bacterial growth and reproduction.1. 大蒜素具有很强的抗菌和抗炎作用,能抑制或杀死各种球菌、杆菌、真菌和病毒。大蒜素对各种致病菌如金黄色葡萄球菌、脑膜炎、肺炎球菌、链球菌、白喉、痢疾、大肠杆菌、伤寒、副伤寒、百日咳、肺结核、霍乱病菌等均有显著的抑制或杀菌作用。大蒜素的抗菌原理是大蒜素分子中的氧原子与半胱氨酸分子中的巯基结合,这是细菌生长繁殖所必需的,抑制细菌生长繁殖。
2. Allicin has inhibitory or killing effects on various pathogenic fungi, including Candida albicans. At low concentrations, it mainly inhibits the growth of fungi, while at high concentrations, it can completely kill fungi. The antifungal mechanism of allicin is to inactivate proteins through thiol oxidation; Competitive inhibition of compounds containing thiol groups such as cysteine and glutathione; Non competitive inhibition of certain enzyme activities within fungi.2. 大蒜素对包括白色念珠菌在内的多种病原菌均有抑制或杀伤作用。在低浓度下,主要抑制真菌的生长,而在高浓度下,它可以完全杀死真菌。大蒜素的抗真菌机制是通过硫醇氧化使蛋白质失活;竞争性抑制含有巯基的化合物,如半胱氨酸和谷胱甘肽;真菌中某些酶活性的非竞争性抑制。
3. Effects on the digestive system Allicin has the ability to reduce nitrite content in the stomach and inhibit nitrate reducing bacteria. Allicin is used to treat chronic stomach diseases, significantly improving symptoms such as stomach discomfort, satiety, dull pain, acid reflux, belching, burning, and loss of appetite. Helicobacter pylori is the main cause of peptic ulcers. Allicin has a significant antibacterial and bactericidal effect on digestive tract bacteria, and has a good therapeutic effect on diarrhea caused by chronic colitis.3. 对消化系统的影响大蒜素具有降低胃中亚硝酸盐含量和抑制硝酸盐还原菌的能力。大蒜素用于治疗慢性胃病,可显著改善胃部不适、饱腹感、钝痛、胃酸反流、打嗝、灼烧和食欲不振等症状。幽门螺杆菌是消化性溃疡的主要原因。大蒜素对消化道细菌有明显的抑菌杀菌作用,对慢性结肠炎引起的腹泻有很好的治疗效果。
4. Protective effect on the liver: The protective mechanism of allicin against chemical liver injury is that allicin can inhibit the damage of lipid peroxides to membrane structure. Allicin can increase the activity of glutathione S-transferase in liver cells, enhance the comprehensive detoxification function of the liver, and thus protect the liver and even the entire organism. Allicin can regulate lipid metabolism membrane transport and cell proliferation by increasing liver cyclic adenosine levels, enhancing enzyme activity, increasing lipid hydrolysis, reducing biosynthesis, increasing lipid component excretion, maintaining serum, liver, and kidney lipoproteins and triglycerides within normal ranges, thereby preventing and controlling fatty liver.4. 对肝脏的保护作用:大蒜素对化学性肝损伤的保护机制是抑制脂质过氧化物对膜结构的破坏。大蒜素可提高肝细胞谷胱甘肽s -转移酶的活性,增强肝脏的综合解毒功能,从而保护肝脏乃至整个机体。大蒜素通过增加肝脏环腺苷水平,增强酶活性,增加脂质水解,减少生物合成,增加脂质成分排泄,维持血清、肝脏、肾脏脂蛋白和甘油三酯在正常范围内,调节脂质代谢、膜转运和细胞增殖,从而预防和控制脂肪肝。
5. Allicin is a good immune stimulating herb. In the experiment on the effect of allicin on mouse immune function, it was found that the weight of spleen and thymus increased in the medication group, T lymphocyte activation increased, the number of antibody forming cells in the spleen increased, the secretion level of monocytes increased, and lysozyme release increased. Therefore, allicin can improve cellular immunity, humoral immunity, and non-specific immune function. 5. 大蒜素是一种很好的免疫刺激草药。在大蒜素对小鼠免疫功能影响的实验中,发现给药组小鼠脾脏和胸腺重量增加,T淋巴细胞活化增加,脾脏内抗体形成细胞数量增加,单核细胞分泌水平增加,溶菌酶释放增加。因此,大蒜素可以提高细胞免疫、体液免疫和非特异性免疫功能。
The use of allicin can be added to feed and mixed, which has the effect of increasing animal appetite. Be careful not to use allicin together with antibiotics.使用大蒜素可以在饲料中添加和混合,有增加动物食欲的作用。注意不要与抗生素一起使用大蒜素。使用大蒜素可以在饲料中添加和混合,有增加动物食欲的作用。注意不要与抗生素一起使用大蒜素。
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